Antioch was one of the most important cities in the early history of the Church. Located in Syria, it became a central hub for Gentile missions and a model of church life and outreach. After the persecution that followed Stephen’s martyrdom, believers scattered and preached the gospel, and Acts 11:20-21 records that in Antioch, “a great number believed and turned to the Lord.”
The church at Antioch quickly became known for its faith and generosity. When a famine was prophesied, the disciples there “each according to his ability, determined to send relief to the brethren dwelling in Judea” (Acts 11:29).
It was in Antioch that the disciples were first called Christians (Acts 11:26), marking a significant moment of identity for the followers of Jesus. The church was a blend of Jews and Gentiles, rich in the Word and active in the Spirit.
Antioch also served as the launching point for Paul’s missionary journeys. Acts 13:1-3 records how the Holy Spirit directed the church there to send out Barnabas and Saul. This church became a sending base for evangelism throughout the Roman world.
Later, Antioch was the setting of a notable confrontation between Paul and Peter over the issue of Gentile fellowship and the hypocrisy of separating from them (Galatians 2:11-14), showing that even strong churches must guard their doctrine and conduct.
Antioch represents a church alive with teaching, missions, and bold witness. A pattern of what the body of Christ should be.